Gelatin Capsule Dissolution In Vitro and In Vivo (Cow)

For dissolution in non-pharmaceutical applications contact us.

Capsule Dissolution Time: In Vitro

Dissolution in 37C (98F) Water


Capsule Dissolution Time: In-Vivo Data

Dissolution of a Size 7 Capsule filled with Lactose Powder in a Fistulated Cow

The photograph above clearly shows that a Size 7 gelatin capsule is dissolved rapidly by the rumen contents within 10 - 15 minutes.

Further, the rate controlling step in bioavailability of materials dosed via gelatin capsules is the nature of the material itself and not the delivery system or excepients.  The photographs are of a Torpac Gelatin Capsule removed from a fistulated cow 5, 10, and 15 minutes after placement.

For further information and a copy of the test study, please contact Torpac.

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